There may be a biological reason for our preference for harmony. Via Wired:

“Over the past century, researchers have tried to relate the perception of dissonance to the underlying acoustics of the signals,” says psychoacoustician Marion Cousineau of the University of Montreal in Canada. In a musical chord, for example, several notes combine to produce a sound wave containing all of the individual frequencies of each tone. Specifically, the wave contains the base, or “fundamental,” frequency for each note plus multiples of that frequency known as harmonics. Upon reaching the ear, these frequencies are carried by the auditory nerve to the brain. If the chord is harmonic, or “consonant,” the notes are spaced neatly enough so that the individual fibers of the auditory nerve carry specific frequencies to the brain. By perceiving both the parts and the harmonious whole, the brain responds to what scientists call harmonicity.

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